Seoul National University Pituitary Disease Cohort Study

Study Purpose

The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary tumor tissue (when available through clinical care) will be saved for future analyses related to pituitary disease.

Recruitment Criteria

Accepts Healthy Volunteers Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms	No
Study Type An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies.	Observational
Eligible Ages	18 Years and Over
Gender	All

More Inclusion & Exclusion Criteria

Inclusion Criteria:

- Subjects for this study will be recruited if they are: 1.

Adults, male or female aged 18 years or older. 2. diagnosed with pituitary diseases such as acromegaly, Cushing's disease, hyperprolactinemia, nonfunctioning pituitary adenoma, pituitary stalk lesions, central diabetes insipidus, and craniopharyngiomas.

Exclusion Criteria:

- Patients who do not agree with the study

Trial Details

Trial ID: This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.	NCT03474601
Phase Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.
Lead Sponsor The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.	Seoul National University Hospital
Principal Investigator The person who is responsible for the scientific and technical direction of the entire clinical study.	Jung Hee Kim, M.D
Principal Investigator Affiliation	Seoul National University Hospital
Agency Class Category of organization(s) involved as sponsor (and collaborator) supporting the trial.	Other
Overall Status	Recruiting
Countries	Korea, Republic of
Conditions The disease, disorder, syndrome, illness, or injury that is being studied.	Pituitary Disease, Pituitary Incidentaloma, Acromegaly, Central Diabetes Insipidus, Pituitary Stalk Compression Hyperprolactinaemia, Cushing's Disease, Pituitary Tumor, Prolactinoma

Additional Details

Subjects for this study will be recruited if they are: 1. Adults, male or female aged 18 years or older. 2. Have been diagnosed with pituitary diseases

Arms & Interventions

Arms

: Acromegaly

Patients diagnosed with acromegaly

: Cushing's disease

Patients diagnosed with Cushing's disease

: Hyperprolactinemia/prolactinomas

Patients diagnosed with hyperprolactinemia/prolactinoma

: Pituitary stalk lesions

Patients diagnosed with pituitary stalk lesions

: Nonfunctioning pituitary adenomas

Patients diagnosed with nonfunctioning pituitary adenomas

: Central diabetes insipidus

Patients diagnosed with central diabetes insipidus

: Craniopharyngioma

Patients diagnosed with craniopharyngiomas

: Others

Patients diagnosed with other suprasellar/parasellar lesions

Interventions

Other: - Dynamic hormone study and Magnetic resonance imaging

Medical history Imaging examination including brain magnetic resonance imaging Blood (Basal hormone study and follow-up study) and pituitary tumor tissue

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.